The telecom industry collapsed with cheap bandwidth.
The Recording Industry and Motion Pictures industry found their business models outdated with the advent of MP3s, Napster and P2P file sharing.
The publishing industry is struggling in the wake of the onslaught of blogs and online newscasts.
The next casualty is going to be the mortgage industry -- Prosper, Zopa, Lending Club and others are making it easy to borrow small amounts of money. How long before greedy realtors, who merely "provide access to money with no fiduciary responsibility", are out of business?